A novel coronavirus capable of lethal human infections: an emerging picture.
Identifieur interne : 001A02 ( Main/Exploration ); précédent : 001A01; suivant : 001A03A novel coronavirus capable of lethal human infections: an emerging picture.
Auteurs : Gulfaraz Khan [Émirats arabes unis]Source :
- Virology journal [ 1743-422X ] ; 2013.
Descripteurs français
- KwdFr :
- Coronavirus (), Coronavirus (génétique), Coronavirus (isolement et purification), Humains, Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Maladies transmissibles émergentes (virologie), Maladies transmissibles émergentes (épidémiologie), Moyen Orient (épidémiologie), Pakistan, Royaume-Uni (épidémiologie).
- MESH :
- génétique : Coronavirus.
- isolement et purification : Coronavirus.
- virologie : Infections à coronavirus, Maladies transmissibles émergentes.
- épidémiologie : Infections à coronavirus, Maladies transmissibles émergentes, Moyen Orient, Royaume-Uni.
- Coronavirus, Humains, Pakistan.
English descriptors
- KwdEn :
- Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (virology), Coronavirus (classification), Coronavirus (genetics), Coronavirus (isolation & purification), Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Humans, Middle East (epidemiology), Pakistan, United Kingdom (epidemiology).
- MESH :
- classification : Coronavirus.
- epidemiology : Communicable Diseases, Emerging, Coronavirus Infections, Middle East, United Kingdom.
- genetics : Coronavirus.
- isolation & purification : Coronavirus.
- virology : Communicable Diseases, Emerging, Coronavirus Infections.
- Humans, Pakistan.
Abstract
In September 2012, a novel coronavirus was isolated from a patient in Saudi Arabia who had died of an acute respiratory illness and renal failure. The clinical presentation was reminiscent of the outbreak caused by the SARS-coronavirus (SARS-CoV) exactly ten years ago that resulted in over 8000 cases. Sequence analysis of the new virus revealed that it was indeed a member of the same genus as SARS-CoV. By mid-February 2013, 12 laboratory-confirmed cases had been reported with 6 fatalities. The first 9 cases were in individuals resident in the Middle East, while the most recent 3 cases were in family members resident in the UK. The index case in the UK family cluster had travel history to Pakistan and Saudi Arabia. Although the current evidence suggests that this virus is not highly transmissible among humans, there is a real danger that it may spread to other parts of the world. Here, a brief review of the events is provided to summarize the rapidly emerging picture of this new virus.
DOI: 10.1186/1743-422X-10-66
PubMed: 23445530
Affiliations:
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Le document en format XML
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The clinical presentation was reminiscent of the outbreak caused by the SARS-coronavirus (SARS-CoV) exactly ten years ago that resulted in over 8000 cases. Sequence analysis of the new virus revealed that it was indeed a member of the same genus as SARS-CoV. By mid-February 2013, 12 laboratory-confirmed cases had been reported with 6 fatalities. The first 9 cases were in individuals resident in the Middle East, while the most recent 3 cases were in family members resident in the UK. The index case in the UK family cluster had travel history to Pakistan and Saudi Arabia. Although the current evidence suggests that this virus is not highly transmissible among humans, there is a real danger that it may spread to other parts of the world. 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